Our Purpose: EMPOWER CELLS TO CHANGE LIVES? At SQZ Biotechnologies we believe that our cell therapies will revolutionize the way we treat diseases. Our unique capabilities enable us to engineer almost any function into any cell type, breaking down the barriers in the field, and creating the possibility for cell therapies that could not have been previously envisioned.? ?Our Values:? Squeeze Together: We value teamwork, trust, and transparency as critical components for achieving our mission and exceeding our goals?Question Boundaries: We're committed to questioning the status quo and changing the world through our people and our science?Zap Obstacles: We strive to be pioneers. We're resilient when it comes to navigating challenges, anticipated or not, scientific and otherwise? The Role:
SQZ Biotechnologies is seeking a flexible, detail oriented analytical thinker as a Research Associate to join the Analytical Development & Quality Control (AD&QC) team. The successful candidate will work within the internal AD&QC team to develop analytical methodologies for characterization of SQZ Biotechnology's cell therapy products, support internal testing needs, and work collaboratively with Research and Development teams. The successful candidate will also work with external partners to transfer and qualify appropriate test methods.??Responsibilities:
Contribute to the development of:Flow cytometry methods to characterize cell therapy products, including elucidation of cell composition for blood products, in-process samples and product materialsCell counting and cell viability methods suitable for deployment in CMC manufacturing settingsAnalytical methods to measure potency of cell therapy productsAnalytical methods for heightened characterization of cellular, donor-based starting materials?Conduct studies to understand stability profile of cell therapy productsSupport external method transfer and analytical method qualification activities at contract manufacturing organizations (CMOs)Perform QC activities on materials generated by internal process development team; provide testing support for research and exploratory teams as needed?Candidate Must:?Independently execute and troubleshoot experiments?Manage multiple projects simultaneouslyDiligently document all data in electronic notebooks in a timely mannerCritically analyze and present data?Demonstrate critical thinking, problem solving and attention to detailEffectively plan, organize, and schedule work activities to meet deadlinesWork collaboratively in a high-impact team setting?Minimum Qualifications:?
BS or MS in life science or related field (Cell Biology, Biochemistry, Bioengineering, etc.)At least least 1 year of cumulative experience in an industry setting preferredExpertise in aseptic techniqueExperience with cell characterization methods and instrumentation (e.g. flow cytometry, FACS, cell counting and viability, hematology analyzers, plate readers)Good understanding of safe lab practices and BSL requirementsExcellent computer skills including experience with Excel, Minitab, GraphPad Prism or similar statistical and data analysis software Preferred Qualifications
Experience with diverse analytical, molecular biology and immunological methods (e.g. U/HPLC, ELISA, ELISpot, Fluorescence and/or Confocal Microscopy, IF/ICS, IHC, FACS, gel electrophoresis, western blot, qPCR)Experience with analytical method qualification and validationsExperience with data processing software like FlowJo, SoftMax Pro, or chromatography analysis softwareExperience writing scientific reports and method SOPs SQZ Biotechnologies is proud to be an equal opportunity employer and to provide equal opportunities to all employees and applicants for employment without regard to race, color, religion, sex or gender identity, national origin, age, disability, sexual orientation or genetics. In addition to federal law requirements, SQZ complies with applicable state and local laws governing nondiscrimination in employment. SQZ does not support relocation for this role.?