Cyprotex, part of the Evotec group are recruiting a Senior Research Scientist to join our Bioanalytical Team based at Alderley Park, Cheshire, UK. The Bioanalytical team supports in vivo discovery pk studies, bioanalytical discovery projects and bespoke method development activities.
Responsibilities: The primary responsibilities include but are not limited to:
Development of customised LC-MS/MS methods for analysis of potentially challenging compounds in a range of biological matrices including utilisation of reverse phase and Hilic chromatography
Troubleshooting and system maintenance and co-ordination of engineer visits MS/MS and UPLC process optimisation for compounds using automated tools and established processes
Leading training of more junior team members and contributing to scientific knowledge sharing.
Contributing to our Quality System via preparation and review of SOPs Collaborating effectively with our Information Systems Team to design and implement automation and data processing tools.
Seeking opportunities to form additional collaborative relationships
Promote and support a continuous improvement culture
Additional Responsibilities may include:
Line management including personal development of direct reports
Scheduling of lab activities and resources for bespoke bioanalytical activities Flexing into other analytical areas to provide resource/cover given suitable training and supervision
Working with assay scientists to maximise quality and throughput Knowledge,
Skills and Abilities Essential:
Hands-on experience of utilising LC-MS/MS techniques for analysis of small and large molecules in preclinical samples from within a discovery, development or CRO setting
Proven record of accomplishment in bioanalytical method development including good knowledge of MS, chromatography and sample preparation techniques.
The ability to perform routine maintenance on LC-MS/MS equipment
A high level of attention to detail and well organised with an ability to work without close supervision
Ability to adapt to changing priorities, manage multiple activities simultaneously and to achieve timelines
Motivational team player with a high level of dedication
Extensive computer literacy including use of Microsoft Office Ability to rapidly learn new techniques and processes
Preferred but not essential
Advanced LC-MS/MS maintenance skills. Experience with MassLynx , Analyst or other Mass Spectrometry data acquisition software packages.
A wider knowledge of analytical support in drug discovery/development (e.g bioanalytical method validation)
A knowledge of DMPK/ADME assays within drug discovery/development
Qualifications Minimum BSc in relevant scientific discipline covering chemistry.
Rewards and Benefits Cyprotex aims to encourage, support and recognise the excellent performance and behaviour of our colleagues. Our performance-based compensation policy applies to all colleagues of the Evotec Group companies. We offer a variety of benefits, which include amongst others, excellent pension benefits and service related holidays. We recognise that our colleagues have full lives away from the workplace and support working patterns that balance private life and career.
Career Development As part of the Evotec Group, we grow through innovation, collaboration, nurturing our people and continuing to develop as a world-class organisation.
We aim to recruit and retain the best because our work is challenging and requires the most competent staff. We look for talented individuals from all walks-of life, educational backgrounds and nationalities, to provide the expertise and dedication to enable us to achieve continual success in everything we do. We offer equal opportunities for people with or without, visible or not-visible disabilities.
If you are keen to be a part of our successful and growing global business, please upload an up-to-date CV and covering letter via the website using the following link:
The closing date for receipt of applications is 5pm on Friday, 26th July 2019. Applicants will need to be available for interview w/c 5th August 2019.
Direct applications only no agencies please.
* The salary listed in the header is an estimate based on salary data for similar jobs in the same area. Salary or compensation data found in the job description is accurate.